25246774
OBJECTIVE	The objective of the current study was to evaluate the efficacy of aminaphtone to control gum bleeding .
METHODS	Fifteen male and 15 female children , aged between 10 and 18 years with a mean age of 13.4 years and with gingival bleeding , were enrolled in this randomized , double-blind , placebo-controlled , Phase IV clinical trial .
METHODS	The inclusion criterion was gingivitis with gingival bleeding .
METHODS	Participants were prescribed either aminaphtone or placebo .
METHODS	Thirty identical boxes containing blister packs of identical pills of either aminaphtone or placebo were produced and coded with unique numbers by the manufacturer ( Baldacci Laboratory , Brazil ) and donated for this trial .
METHODS	A research assistant administered aminaphtone ( Capilarema 75 mg ) to fifteen patients or placebo to fifteen patients twice daily for 5 days .
METHODS	Intraoral clinical evaluations of bleeding were made before starting medication/placebo and then at 3 and 5 days after administration .
RESULTS	On comparing the number of bleeding points before and after treatment between the aminaphtone and placebo groups , we found significantly higher reductions with the medication ( P < 0.0001 ) .
CONCLUSIONS	Aminaphtone reduces gum bleeding in gingivitis , and may have a supportive role in the control of bleeding .

