25602877
OBJECTIVE	We ( 1 ) evaluated the impact of an evidence-based HIV prevention program with and without a parent component among mid-adolescents living in the Caribbean and ( 2 ) determined the effect of prior receipt of a related intervention during preadolescence on intervention response .
METHODS	A randomized , controlled 4-cell trial of a 10-session , theory-based HIV prevention intervention involving 2564 Bahamian grade-10 youths ( some of whom had received a comparable intervention in grade 6 ) was conducted ( 2008-2011 ) .
METHODS	Randomization occurred at the level of the classroom with follow-up at 6 , 12 , and 18 months after intervention .
METHODS	The 3 experimental conditions all included the youths ' curriculum and either a youth-parent intervention emphasizing adolescent-parent communication , a parent-only goal-setting intervention , or no parent intervention .
RESULTS	An intervention delivered to mid-adolescents in combination with a parent-adolescent sexual-risk communication intervention increased HIV/AIDS knowledge , condom-use skills , and self-efficacy and had a marginal effect on consistent condom use .
RESULTS	Regardless of prior exposure to a similar intervention as preadolescents , youths benefited from receipt of the intervention .
CONCLUSIONS	Preadolescents and mid-adolescents in HIV-affected countries should receive HIV prevention interventions that include parental participation .

