24796048
OBJECTIVE	To evaluate the efficacy and safety of acupuncture-moxibustion combined with modified Mojie tablet ( see text ) in the prevention of the recurrence of endometriosis ( EMS ) after laparoscopic surgery .
METHODS	After laparoscopic surgery , 120 cases of EMS were randomized into an acupuncture-moxibustion group , a western medication group , a Chinese medication group and a combined therapy of acupuncture-moxibustion and Chinese medication group ( combined therapy group ) , 30 cases in each one .
METHODS	In the acupuncture-moxibustion group , acupuncture was applied at Xuehai ( SP 10 ) , Sanyinjiao ( SP 6 ) and Guanyuan ( CV 4 ) ; the isolated moxibustion with ginger was used at Guanyuan ( CV 4 ) , once a day , twice a week .
METHODS	In the western medication group , gestrinone was prescribed for oral administration , 2.5 mg , once a day , twice a week .
METHODS	In the Chinese medication group , the self-prepared Mojie tablet were prescribed for oral administration .
METHODS	In the combined therapy group , acupuncture , moxibustion and modified Mojie tablet for oral administration were used in combination .
METHODS	The therapeutic methods were same as the acupuncture-moxibustion group and the Chinese medication group .
METHODS	Totally , the treatment of 3 months was required .
METHODS	Separately , before treatment , after treatment , in 3 months after treatment and in 6 months after treatment , EHP-5 score ( endometriosis health profile-5 ) , the abdominal/vaginal ultrasound examination , serum CA125 detection and safety index ( ALT detection ) were compared in patients among 4 groups .
RESULTS	In 3 and 6 months after treatment , the positive rates of EHP-5 score were 0 % ( 0/30 ) in the combined therapy group and 0 % ( 0/30 ) in the acupuncture-moxibuston group , which were all lower significantly than 13.3 % ( 4/30 ) in the western medication group ( both P < 0.05 ) .
RESULTS	In follow-up stage of 6 months after treatment , there was no recurrence case in abdominal lviginal ultrasound examination in the combined therapy group , which was lower than 13.3 % ( 4/30 ) in the western medication group ( P < 0.05 ) ; the serum CA125 detection in the combined therapy group did not find any abnormal case , which was lower than 16.7 % ( 5/30 ) in the western medication group ( P < 0.05 ) .
RESULTS	At the end of treatment session and in the follow-up stage of 3 months after treatment , the abnormal rate of ALT were 20.0 % ( 6/30 ) and 13.3 % ( 4/30 ) in the western medication group , which were higher than those in any of the rest groups ( P < 0.05 ) .
RESULTS	In the follow-up stage of 6 months after treatment , there were 3 abnormal cases of ALT in the western medication group , but which was not different significantly as compared with the rest groups ( P > 0.05 ) .
CONCLUSIONS	Acupuncture and moxibustion combined with modified Mojie tablet effectively prevent from the recurrence of EMS after laparoscopic surgery and improve the life quality of the patients .
CONCLUSIONS	This combined therapy brings less damage on the liver as compared with the western medication of gestrinone and indicates its definite efficacy and safety .

